On a flight gone wrong, one patient’s life is quite literally turned upside down.

Dr. Wolf helps a firefighter and his family navigate a life-changing diagnosis on Thanksgiving.

Dr. Wolf helps a ballerina recover after a mystery illness. The team tries to save Sam's life and get him on the transplant list.

Dr. Oliver Wolf reluctantly accepts a job at Bronx General Hospital where he's forced to work with a team of interns as they treat a mother who can no longer recognize her kids.

When a high school girls’ basketball coach is faced with a debilitating illness, Dr. Wolf must help his patient reconnect with her body before it’s too late.

A member of a biker gang seeks out Wolf's help as he grapples with life-threatening memory loss.

When a bloody bride stumbles into Bronx General, Wolf goes to extreme measures in a race against the clock to save her and her missing husband.

Wolf must help a Marine grapple with mysterious symptoms before the birth of his child.

Dr. Wolf and the interns go back to high school to treat a group of pregnant teenagers.

Dr. Wolf and the team perform their most experimental treatment yet: a brain computer interface implantation in their John Doe patient's brain.

When an elderly woman is brought in with signs of dementia, Dr. Wolf investigates whether she's suffering from a neurological disorder or having a late-in-life awakening.

When an artist refuses to paint for his upcoming show, Dr. Wolf and his team must figure out why. Dr. Pierce goes into uncharted territory with a patient.

An unexpected patient crashes into Bronx General with mysterious life-threatening symptoms.

Dr. Pierce treats a patient in crisis, presenting an ethical dilemma. Dr. Wolf and Dr. Nichols disagree on how to treat a patient.

Dr. Wolf and his team face their biggest challenge yet when an apartment building collapses in the Bronx.

Dr. Wolf meets a pastor dealing with mysterious visions. The interns grapple with the fallout from the building collapse.

Dr. Wolf helps an MMA fighter with mysterious symptoms. Dr. Pierce considers a career outside of Bronx General.

A reality show contestant lands at the hospital with an unusual delusion. Dr. Pierce fights for her future at Bronx General.

Dr. Wolf and his team treat a young patient accused of a serious crime.

Dr. Wolf and Dr. Pierce are tasked with a house call to evaluate a woman under a conservatorship. Dr. Kinney's curiosity is piqued by a patient outside the hospital.

When two patients arrive in critical condition, Dr. Wolf and Dr. Nichols must do whatever it takes to keep them alive.

Dr. Wolf is haunted by a ghost from his past. A patient arrives at Bronx General who appears to have risen from the dead.

A blast from the past shakes up Dr. Wolf's world when he becomes his next patient.