The ponies share adventures and help out other residents of Ponyville, while working out the troublesome moments in their own friendships.
After attempting to warn Princess Celestia about the return of the wicked Night Mare Moon, Twilight Sparkle and Spike travel to Ponyville where they meet Pinkie Pie, Applejack, Rainbow Dash, Rarity and Fluttershy.
It is up to Twilight and her new pony friends to help the Princess, but it will not be easy. Night Mare Moon challenges the ponies with individual obstacles they must overcome to find the Elements of Harmony before it is too late.
When Twilight Sparkle receives two tickets from Princess Celestia to the Grand Galloping Gala, all of her friends want to go�but who will she choose?
It�s Applebuck Season in Ponyville and a short-handed Applejack is determined to complete the harvest all by herself.
Pinkie Pie and Rainbow Dash pal around playing pranks on the other ponies, but when Dash�s old friend Gilda the Griffon shows up, Pinkie Pie suddenly becomes a third wheel.
The arrival of Trixie, a boastful pony with magical skills, irritates the ponies in Ponyville who turn to Twilight to challenge her.
Fluttershy must convince a sleeping dragon to move out of town before the plume of black smoke it�s producing covers all of Equestria!
When the ponies gather at Twilight�s for a slumber party, Rarity and Applejack begin to quarrel and threaten to ruin the party.
When the ponies are afflicted with bizarre and humorous sicknesses they accuse a mysterious zebra named Zecora of placing a curse on them.
Parasprites, furry little multiplying creatures, descend upon Ponyville and begin to devour everything and it�s up to the ponies to find a solution.
Twilight Sparkle does her best to prepare for the upcoming Winter Wrap-Up without relying on her magic to help.
Apple Bloom is discouraged because she has not received her cutie mark yet so she aggressively searches out her purpose in life so she can get it.
When Rainbow Dash and Applejack compete against each other in the annual Running of the Leaves, competition turns sour and the ponies do whatever it takes to win.
Rarity offers to make dresses for her friends for the upcoming Gala but gets in over her head when she tries to incorporate all of their individual styling ideas.
Amazed with Pinkie Pie�s ability to predict the future, Twilight Sparkle follows her around in order to uncover the source of her incredible abilities.
When Twilight uses her magic to give Rarity wings so that she can watch Rainbow Dash compete in a race, Rarity is so taken with her new ability that she disrupts the competition.
Fluttershy offers to babysit the Cutie Mark Crusaders but quickly discovers that they are more than she can handle.
The Cutie Mark Crusaders sign up for a talent show hoping to discover their true life meaning and finally earn their cutie marks.
While hunting in the woods for gems for a new dress, Rarity is taken by a group of greedy Diamond Dogs and forced to find jewels for them.
Rarity recruits Fluttershy as a model in hopes of impressing a famous designer with her dresses, but it�s Fluttershy�s modeling career that takes off instead!
The ponies work to settle a complicated land dispute between the Apple-loosans and a herd of buffalo fighting over the same territory.
Without asking permission, Fluttershy borrows the Princess�s sick bird in order to heal it, and the ponies must work together to get it back before she notices.
Frustrated with their lack of success, The Cutie Mark Crusaders seek out Twilight and the rest of the ponies to learn the stories of how they got their cutie marks.
When Twilight becomes friends with an Owl who helps her around the house with chores, Spike becomes jealous and fears he will be replaced.
Confused and discouraged, Pinkie Pie goes on a mission to find out why her friends are avoiding her most recent party invitation.
Expectations are high for the Grand Galloping Gala but when the ponies arrive they find that their individual interests in the Gala are not all they had hoped for.
Discord escapes his imprisonment, steals the Elements of Harmony and sows dissension among Twilight's friends to prevent their recovery.
Finding that the recovered Elements are powerless with her friends magically corrupted by Discord, Twilight Sparkle must rediscover the truth of her friendship to regain hope.
Twilight panics when she can't find a lesson about friendship for her weekly letter to the princess.
It's Nightmare Night in Ponyville, and Princess Luna decides to pay a visit, determined to change her public image for the better.
Sweetie Belle wants to help Rarity out at her shop, but seems to keep messing things up. An upcoming "Sisters" celebration gives her an opportunity to bond with Rarity.
Apple Bloom finally gets her cutie mark, but she panics at unexpected second, third, and more cutie marks.
In order to choose her first pet, Rainbow Dash hosts a flying race.
Rainbow Dash's athletic skill and prowess are earning her much recognition from the citizenry of Ponyville. However, she soon finds her skills being trumped by a mysterious masked pony who some have dubbed, Mare-Do-Well.
Rarity is faced with a decision: Stay with her friends or move to the high social life in Canterlot?
It's Spike's birthday, but his excessive greediness causes him to have a large growth spurt that could destroy Ponyville.
Twilight Sparkle and her friends reenact the story of the founding of Equestria.
Apple Bloom doesn't want Granny Smith to embarrass her by speaking in her class.
Pinkie Pie has been asked by Mr. and Mrs. Cake to watch over their twin toddlers, but finds that it may be harder than she thought it would be.
When Applejack disappears from a Canterlot rodeo competition, her friends set out on a journey throughout Equestria to find her.
The Flim Flam brothers challenge the Apple family to a cider-making contest, and the winner will gain possession of the family's Sweet Apple Acres farm. With their home at stake, the Apples must work together and use all of their cider-making skills to win.
When Rainbow Dash is stuck in the hospital, she discovers the joys of reading, but tries to hide her new hobby from her friends for fear of being an "egghead" herself.
The Cutie Mark Crusaders try to get Cheerilee and Big Macintosh to fall in love with a strong potion, but they quickly regret their actions when some serious side effects arise.
Pinkie Pie tries to make friends with Cranky Doodle Donkey, the only Equestrian to refuse her friendship, only to prove an intolerable pest.
When Fluttershy becomes tired of being pushed around for too long, she decides to seek some assertiveness training from a self-help guru named Iron Will.
When Twilight Sparkle receives a strangely vague warning about impending doom and disaster from her future self, she drives herself nearly mad in an attempt to stall a cataclysmic event, but her uncertainty makes finding answers difficult.
Spike goes on a journey of self-discovery by joining the "Great Dragon Migration," but a raucous gang of teenage dragons might hold the key to the questions Spike has about his identity.
Fluttershy struggles to overcome her fear of public humiliation so she can help Rainbow Dash and the other pegasi create a tornado powerful enough to lift the water required for the rainy season in the cloud-producing city of Cloudsdale.
The Cutie Mark Crusaders start a gossip column under the name Gabby Gums, but find it might not be worth the pain the stories cause other ponies.
An investigation is ordered after a cake Pinkie Pie is guarding for a contest is ruined on the way to Canterlot.
Twilight Sparkle is confused by her conflicting feelings when she finds out her brother, Shining Armor, is marrying Princess Celestia's niece, Cadence.
Shining Armor and Princess Cadence are set to be married, but Twilight Sparkle has just discovered a dark secret about the bride to be.
Northern Equestria's Crystal Empire has reappeared after being afflicted with a curse that made it vanish for 1,000 years. Princess Celestia asks Twilight Sparkle and her friends to protect the empire from disappearing again.
After Princess Celestia commissions her to keep Crystal Empire from vanishing again, Twilight realizes that she must find the missing Crystal Heart in order to restore the empire's reputation and strength before it disappears again.
Overwhelmed with having to choose just one friend to spend time with, Pinkie Pie uses a magic mirror to clone herself.
The Cutie Mark Crusaders are crushed when Apple Bloom's cousin, Babs Seed, rejects their invitation to become a fellow Crusader and instead joins Diamond Tiara and Silver Spoon bullying them.
When Trixie returns to Ponyville, she defeats Twilight and banishes her from town.
Rainbow Dash tells scary campfire stories, which give Scootaloo nightmares, but Scootaloo doesn't want to tell anyone about her bad dreams for fear of being made fun of.
Rainbow Dash receives an invitation to attend the Wonderbolt Academy, but questions whether she is Wonderbolt material.
Granny Smith agrees to let Applejack lead the Apple Family reunion but Applejack loses sight of what is truly important.
After Applejack saves Spike, he insists on fulfilling the Noble Dragon Code by repaying her with excessive help around the farm.
The Mane Six, especially Fluttershy, are commanded by Princess Celestia to attempt to reform Discord.
To earn gemstones, Spike persuades the Mane Six to let him take of their pets while they are away at the Crystal Empire.
Twilight Sparkle and her friends are assigned to persuade the Equestria Games inspector to select the Crystal Empire.
When Twilight casts a spell that switches her friends' cutie marks and destinies, the only way to reverse the spell is by inventing her own magic.