Following years of land encroachments by American settlers, Chief Little Turtle of the Miami leads the Indian Nations of the Northwest Confederacy to a major victory over the fledgling U.S. Army.

After building his reputation as a formidable hunter on Lewis and Clark's Expedition into the newly acquired Louisiana Territory, John Colter chooses to stay out in the wilderness and enter the booming fur trade.

After braving the Oregon Trail and settling near the Columbia River, Protestant missionaries Marcus and Narcissa Whitman seek to spread their Christian faith and bring their way of life to the local Cayuse people.

The abduction of nine-year-old Cynthia Ann Parker kicks off a series of increasingly deadly confrontations between her Comanche captors and the newly independent Texas.

In Gold Rush California, Mexican immigrant Joaquin Murrieta forms a gang of outlaws that spreads terror across the newly formed state. A posse of California Rangers, led by the fearsome Harry Love, takes Murrieta down.

When Kansas becomes a battleground in the national debate over slavery, settlers on both sides of the issue pour into the territory to determine its future as a free or slave state in its eventual admission to the Union.

When Civil War veteran Col. Henry Carrington takes command of Fort Phil Kearny in Northern Wyoming, he never expects to face such a ferocious enemy as Red Cloud's band of Lakota Sioux.

In the fertile expanse of Northern Wyoming's Powder River Valley, a group of small-time ranchers led by Nate Champion band together to protect their rights to graze cattle on the open range.