In 2003 Zoe Jacobs disappeared from the picturesque town of Moorevale during her own 21st birthday party. She packed her things into a blue backpack and walked out, withdrawing all her cash and leaving behind a note.

George Stanley argues with his wife at her hair salon, leaves to deposit the day's earnings and never returns.

While searching for Julie Cochran, a Manhattan-based woman who disappeared on the morning she was scheduled to leave town, the team soon suspects her live-in boyfriend, Greg Knowles.

After Martin's Aunt Bonnie, a feeble cancer patient and nurse, vanishes for several hours, her concerned husband and adult daughters summon Martin to help find her.

The team searches for Mark Wilson, who disappeared while trying to prove the innocence of his death-row inmate son, Ricky, scheduled to die in two days.

The team searches for college football coach Jim Cooper, who goes missing after being terminated for his team's unusually dismal season performance.

Jack and his team try to determine if foul play was involved in the 1991 adoption of 16-year-old Serene Barnes after the teen shows up at the FBI offices claiming she was kidnapped as a young child.

On Jack's last case before he moves to Chicago, the team searches for a billionaire's estranged wife and their two children after the yacht they were last seen boarding is soon found adrift in New York Harbor--with only its dead captain aboard.

While searching for a missing nurse's aide, who disappeared from a rural road while changing a flat tire, the team discovers that this woman is actually a fugitive wanted for bombing an abortion clinic.

While searching for missing 37-year-old X-ray technician Teddy Cota, the team discovers that Teddy long believed that when he was a child, he was abducted by aliens.

Jack and the team must determine if a missing nanny is a kidnapping victim or a suspect when she and the infant in her care disappear from her employers' home.

Lynette Shaw, the physically transformed winner of the popular surgical makeover reality show "American Goddess," disappears in the midst of a publicity event.

The team searches for Colleen McGrath, a struggling, young, single mother who vanishes after leaving her 3-year-old son in his baby-sitter's care.

In a continued effort to find Colleen McGrath, a missing young mother who had recently been recruited as a drug mule, Samantha goes undercover as a woman with similar grim financial circumstances hoping to be approached by the same drug traffickers.

When a homeless woman goes missing from a shelter linked to a previous case, Jack suspects Rick Knowles -one of two identical twins--who manipulated his brother, Greg, into confessing to the murders of several other homeless women.

Jack and the team search for Peter Dusek, a wealthy, 72-year-old murder trial juror, whose disappearance could cause a mistrial.

The missing man's pregnant ex-girlfriend explains that she ended her relationship with him after he confessed that he feared the extraterrestrials would return for him and their baby.

Jack and the team search for Tara Patterson school student who was last seen by her friends at a bus stop.

While searching for convict James "Mac" MacAvoy, who disappeared during a prison yard fight, the team attempts to determine whether he's a cunning escapee or the victim of a sinister inside plot.

Jack and the team investigate the disappearance of a 12-year-old autistic boy who ran away during a class trip to a museum.

Jack and the team investigate the disappearance of Rosie Diaz, a postal employee.

Jack and the team investigate the disappearance of Chelsea Prince, a 23-year-old society girl known for her constant partying and headline-grabbing escapades.

As the clues pile up, Alberg’s instincts tell him there’s a larger pattern at play… and that he and his team are up against a serial killer.

On Christmas Eve in a quiet town, elderly couple Bob and Idella Young are brutally slain at home.

A mother is brutally shot to death while driving her sons home from a Thanksgiving celebration. When the hunt for her killer leads to an unlikely suspect, investigators soon realize her murder is not as random as it once seemed.

2001: A dismembered corpse is found floating in trash bags in Galveston Bay, Texas. Police trace the body back to a grisly crime scene, and arrest Robert Durst, scion of New York's billionaire real estate family, for the killing of his neighbour, Morris Black.

2013: Durst's interview with Jarecki begins with his childhood, when he witnessed his mother's suicide.... Fast forward to 1982, Robert and Kathie have been married 10 years when Durst walks into the 20th Precinct and says he hasn't seen his wife in five days.

2000: When a random tip leads Westchester County DA Jeanine Pirro to re-open the investigation into the disappearance of Kathie Durst, her investigators focus on Susan Berman, the daughter of a famous Las Vegas mobster, and a witness the police overlooked back in 1982.

As the clues pile up, Alberg’s instincts tell him there’s a larger pattern at play… and that he and his team are up against a serial killer.