An inter-species group of outsiders faces drama when given the ability to communicate with one another.

An African-American woman becomes an unwitting pioneer for medical breakthroughs when her cells are used to create the first immortal human cell line in the early 1950s.

An octogenarian couple returns to Room 104 to relive their first night together.

Tony and Carmela quarrel over the prospect of sending A.J. to military school after he is expelled. Ralphie is forced to make a decision about Jackie, while Meadow reflects upon her life as a Soprano.

Janette, Aunt Mimi and Annie commit to new deals, with varying degrees of enthusiasm; Toni may have found the killer she seeks, but Terry is still looking for his; L.P. meets his victim's family; Antoine plays his bone in Texas; Sonny plays his music closer to home.

Antoine does a good deed, while someone suspects Nelson's deeds may not be so good; Davis fails to sign "Sugar Boy" Crawford for his opera, but Delmond gets his father to sign up with the New Orleans Musicians' Clinic; L.P. learns his headless skeleton wasn't always so.

An octogenarian couple returns to Room 104 to relive their first night together.

Baltimore homicide detective Jimmy McNulty gets into hot water and winds up assigned to a detail of narcotics outcasts investigating drug lord Avon Barksdale. Meanwhile, Avon's nephew D'Angelo, fresh off beating a murder rap, is demoted upon his return to the gang.

McNulty feels the heat when a witness who testified against D'Angelo is found murdered. Meanwhile, Greggs is given the lay of the land regarding Avon Barksdale's key players, and Herc, Carver and Prez find big-time trouble at the towers.

Drama finds out he's to be the target on Pauly Shore's new Punk'd-like reality show. Eric attempts to smooth out tensions between Vince and Amanda, but they've already been relieved. Ari finds himself jealous of his frat brother's newfound riches, as well as his fiance.

An inter-species group of outsiders faces drama when given the ability to communicate with one another.

Through depositions with the newsroom staff, Rebecca pieces together the events that led to ACN's fateful decision to go forward with Dantana's special report. The repercussions threaten to ruin News Night while eclipsing breaking news during another 9/11 anniversary.

Janette, Aunt Mimi and Annie commit to new deals, with varying degrees of enthusiasm; Toni may have found the killer she seeks, but Terry is still looking for his; L.P. meets his victim's family; Antoine plays his bone in Texas; Sonny plays his music closer to home.

Antoine does a good deed, while someone suspects Nelson's deeds may not be so good; Davis fails to sign "Sugar Boy" Crawford for his opera, but Delmond gets his father to sign up with the New Orleans Musicians' Clinic; L.P. learns his headless skeleton wasn't always so.

Tony and Carmela both worry about family finances during the recession. Junior faces his own financial woes as his trial approaches. Adriana brings her new friend to dinner. Tony bonds with Christopher by giving him the opportunity to avenge the murder of his father.

An inter-species group of outsiders faces drama when given the ability to communicate with one another.

Time to face the music.

The story of Albert Einstein's general theory of relativity, his relationship with Astrophysicist Arthur Eddington, and the introduction of this theory to the world against the backdrop of the Great War.

A casting change puts Medellin back on the table for Vince. Ari and Nick Rubenstein must broker the deal between Amanda and the studio by day's end, but because it's Yom Kippur they can't use the most important tools of their trade (cell phones) until after sundown.

The animal community gathers for the trial of the century.

In the wake of Leona's refusal to accept the resignations of three top ACN talents, News Night goes forward with its 2012 election-night coverage. Mindful that Charlie wants a screw-up-free evening, Jim weighs the cons of retracting a call he made too soon.

Antoine does the "Cupid Shuffle" as Desiree's mother's house collapses; Annie's visiting parents learn about her record deal; Albert's kids learn about his lymphoma; Toni learns about Sofia's boyfriend; Sofia gets stopped by Officer Billy Wilson; Janette has a reunion.

Sonny rushes, but still misses the boat. Fats Domino tickles Davis' fancy and a few of the ivories. Antoine seeks reading help for Jennifer. Janette endures corporate hell. Toni and L.P. get a witness. Desiree gets a new ally.

Meadow clashes with her parents when she decides to drop out of college and travel to Europe. Christopher is made a capo in Paulie's crew while Paulie serves a jail term. The Feds threaten to send Adriana up for drug possession if she doesn't turn on the Sopranos.

The early-morning 'field interviews' by Herc, Carver and Prez result in a minor riot, a boy losing an eye, and some bad publicity for the department. On the other side of the law, D'Angelo teaches Wallace and Bodie how to play the game... of chess.